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GTF2E2 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P29084
Clone Names 100430304
Peptide ID 100430304
Additional Information
Gene ID 2961
Other Names Transcription initiation factor IIE subunit beta, TFIIE-beta, General transcription factor IIE subunit 2, GTF2E2, TF2E2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14111b was selected from the C-term region of GTF2E2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GTF2E2
Synonyms TF2E2
Function Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00682}
Research Areas
Citations (0)

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Background

GTF2E2 recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

References

Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)Festen, E.A., et al. Am. J. Gastroenterol. 105(2):395-402(2010)Tanaka, A., et al. Genes Cells 14(3):395-405(2009)Jawhari, A., et al. EMBO Rep. 7(5):500-505(2006)Watanabe, T., et al. Mol. Cell. Biol. 23(8):2914-2926(2003)

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$ 80.00
Cat# BP14111b
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