|Other Names||CCAAT/enhancer-binding protein epsilon, C/EBP epsilon, CEBPE|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14112b was selected from the C-term region of CEBPE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.|
|Tissue Location||Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a bZIP transcriptionfactor which can bind as a homodimer to certain DNA regulatoryregions. It can also form heterodimers with the related proteinCEBP-delta. The encoded protein may be essential for terminaldifferentiation and functional maturation of committed granulocyteprogenitor cells. Mutations in this gene have been associated withSpecific Granule Deficiency, a rare congenital disorder. Multiplevariants of this gene have been described, but the full-lengthnature of only one has been determined.
Prasad, R.B., et al. Blood (2009) In press :Papaemmanuil, E., et al. Nat. Genet. 41(9):1006-1010(2009)Bedi, R., et al. Blood 113(2):317-327(2009)Cloutier, A., et al. J. Immunol. 182(1):563-571(2009)Matsushita, H., et al. Oncogene 27(53):6749-6760(2008)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.