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IBSP Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P21815
Clone Names 100507001
Peptide ID 100507001
Additional Information
Gene ID 3381
Other Names Bone sialoprotein 2, Bone sialoprotein II, BSP II, Cell-binding sialoprotein, Integrin-binding sialoprotein, IBSP, BNSP
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14114a was selected from the N-term region of IBSP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BNSP
Function Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
Cellular Location Secreted.
Research Areas
Citations (0)

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The protein encoded by this gene is a major structuralprotein of the bone matrix. It constitutes approximately 12% of thenoncollagenous proteins in human bone and is synthesized byskeletal-associated cell types, including hypertrophicchondrocytes, osteoblasts, osteocytes, and osteoclasts. The onlyextraskeletal site of its synthesis is the trophoblast. Thisprotein binds to calcium and hydroxyapatite via its acidic aminoacid clusters, and mediates cell attachment through an RGD sequencethat recognizes the vitronectin receptor.


Giroux, S., et al. Bone 47(5):975-981(2010)Koller, D.L., et al. J. Clin. Endocrinol. Metab. 95(4):1802-1809(2010)Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Gordon, J.A., et al. J. Cell. Biochem. 107(6):1118-1128(2009)Hwang, Q., et al. BMC Cancer 9, 121 (2009) :

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$ 80.00
Cat# BP14114a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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