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AKR1B10 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O60218
Clone Names 100517004
Peptide ID 100517004
Additional Information
Gene ID 57016
Other Names Aldo-keto reductase family 1 member B10, 111-, ARL-1, Aldose reductase-like, Aldose reductase-related protein, ARP, hARP, Small intestine reductase, SI reductase, AKR1B10, AKR1B11
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14125c was selected from the Center region of AKR1B10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKR1B10
Synonyms AKR1B11
Function Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
Cellular Location Lysosome. Secreted. Note=Secreted through a lysosome-mediated non-classical pathway
Tissue Location Found in many tissues. Highly expressed in small intestine, colon and adrenal gland
Research Areas
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This gene encodes a member of the aldo/keto reductasesuperfamily, which consists of more than 40 known enzymes andproteins. This member can efficiently reduce aliphatic and aromaticaldehydes, and it is less active on hexoses. It is highly expressedin adrenal gland, small intestine, and colon, and may play animportant role in liver carcinogenesis.


Bailey, S.D., et al. Diabetes Care (2010) In press :Kropotova, E.S., et al. Mol. Biol. (Mosk.) 44(2):243-250(2010)Heringlake, S., et al. J. Hepatol. 52(2):220-227(2010)Ravindranath, T.M., et al. J. Immunol. 183(12):8128-8137(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 80.00
Cat# BP14125c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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