|Other Names||Far upstream element-binding protein 1, FBP, FUSE-binding protein 1, DNA helicase V, hDH V, FUBP1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14126c was selected from the Center region of FUBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a ssDNA binding protein that activatesthe far upstream element (FUSE) of c-myc and stimulates expressionof c-myc in undifferentiated cells. Regulation of FUSE by FUBPoccurs through single-strand binding of FUBP to the non-codingstrand. This protein has been shown to function as an ATP-dependentDNA helicase.
Hsiao, H.H., et al. Biochemistry 49(22):4620-4634(2010)Rabenhorst, U., et al. Hepatology 50(4):1121-1129(2009)Malz, M., et al. Hepatology 50(4):1130-1139(2009)Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)Jang, M., et al. Oncogene 28(12):1529-1536(2009)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.