|Other Names||Rabphilin-3A, Exophilin-1, RPH3A, KIAA0985|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14129b was selected from the C-term region of RPH3A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity).|
|Cellular Location||Cell junction, synapse. Membrane; Peripheral membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Exocytosis of neurotransmitters and hormones isfundamental to synaptic neurotransmission and cell-cellcommunication. RAB3A (MIM 179390) is a small G protein that isthought to act at late stages of exocytosis, and RPH3A is a RAB3Aeffector (Lin et al., 2007 [PubMed 17149709]).
Katkoori, V.R., et al. Front. Biosci. 13, 1050-1061 (2008) :Smith, R., et al. J. Neurochem. 103(1):115-123(2007)Lin, C.C., et al. J. Cell. Physiol. 211(2):316-326(2007)Dalfo, E., et al. Neurobiol. Dis. 16(1):92-97(2004)Rastaldi, M.P., et al. Am. J. Pathol. 163(3):889-899(2003)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.