Mouse Mlk4 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8VDG6 |
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Clone Names | 110316273 |
Gene ID | 234878 |
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Other Names | Mitogen-activated protein kinase kinase kinase MLK4, Mixed lineage kinase 4, Mlk4, Kiaa1804 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP14157c was selected from the Center region of Mouse Mlk4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Map3k21 |
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Synonyms | Kiaa1804, Mlk4 |
Function | Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways (By similarity). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Mlk4 activates the JUN N-terminal pathway (By similarity).
References
Katayama, S., et al. Science 309(5740):1564-1566(2005)
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