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COL3A1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P02461 |
|---|---|
| Clone Names | 80722034 |
| Gene ID | 1281 |
|---|---|
| Other Names | Collagen alpha-1(III) chain, COL3A1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | COL3A1 |
|---|---|
| Function | Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. |
| Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the pro-alpha1 chains of type IIIcollagen, a fibrillar collagen that is found in extensibleconnective tissues such as skin, lung, uterus, intestine and thevascular system, frequently in association with type I collagen.Mutations in this gene are associated with Ehlers-Danlos syndrometypes IV, and with aortic and arterial aneurysms. Two transcripts,resulting from the use of alternate polyadenylation signals, havebeen identified for this gene. [provided by R. Dalgleish].
References
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :Taddese, S., et al. Biochim. Biophys. Acta 1804(4):731-739(2010)Jung, S.M., et al. Platelets 21(2):101-111(2010)
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