|Other Names||Histidine decarboxylase, HDC, HDC|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the biosynthesis of histamine from histidine.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the group II decarboxylasefamily and forms a homodimer that converts L-histidine to histaminein a pyridoxal phosphate dependent manner. Histamine regulatesseveral physiologic processes, including neurotransmission, gastricacid secretion,inflamation, and smooth muscle tone.
Gervasini, G., et al. Allergy (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Ercan-Sencicek, A.G., et al. N. Engl. J. Med. 362(20):1901-1908(2010)Jeong, H.J., et al. Cell. Mol. Life Sci. 66(7):1309-1319(2009)Siezen, C.L., et al. Pediatr. Infect. Dis. J. 28(4):333-335(2009)
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