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CIR Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q86X95
Clone Names 70730045
Peptide ID 70730045
Additional Information
Gene ID 9541
Other Names Corepressor interacting with RBPJ 1, CBF1-interacting corepressor, Recepin, CIR1, CIR
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1417a was selected from the N-term region of human CIR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CIR1
Synonyms CIR
Function May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.
Cellular Location Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome
Tissue Location Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas.
Research Areas
Citations (0)

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CIR may modulate splice site selection during alternative splicing of pre-mRNAs. It fegulates transcription and acts as corepressor for RBPSUH. It recruits RBPSUH to the Sin3-histone deacetylase complex (HDAC) and is required for RBPSUH-mediated repression of transcription.


Olsen,J.V., Cell 127 (3), 635-648 (2006)Maita,H., Exp. Cell Res. 303 (2), 375-387 (2005)Zhou,S., Mol. Cell. Biol. 21 (18), 6222-6232 (2001)

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$ 80.00
Cat# BP1417a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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