|Other Names||MICOS complex subunit MIC27, Apolipoprotein O-like, Protein FAM121A, APOOL, CXorf33, FAM121A, MIC27|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CXorf33, FAM121A, MIC27|
|Function||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:23704930), (PubMed:25764979).|
|Cellular Location||Mitochondrion inner membrane; Multi- pass membrane protein. Mitochondrion|
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Provided below are standard protocols that you may find useful for product applications.
Belongs to the apolipoprotein O family.
Olsen, J.V., et al. Cell 127(3):635-648(2006)Ross, M.T., et al. Nature 434(7031):325-337(2005)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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