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UBA7 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P41226
Clone Names 100430168
Peptide ID 100430168
Additional Information
Gene ID 7318
Other Names Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-activating enzyme 7, D8, Ubiquitin-activating enzyme E1 homolog, UBA7, UBE1L, UBE2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBA7
Synonyms UBE1L, UBE2
Function Activates ubiquitin by first adenylating with ATP its C- terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin- E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein.
Tissue Location Expressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines
Research Areas
Citations (0)

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The modification of proteins with ubiquitin is animportant cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least threeclasses of enzymes: ubiquitin-activating enzymes, or E1s,ubiquitin-conjugating enzymes, or E2s, and ubiquitin-proteinligases, or E3s. This gene encodes a member of the E1ubiquitin-activating enzyme family. The encoded enzyme is aretinoid target that triggers promyelocytic leukemia (PML)/retinoicacid receptor alpha (RARalpha) degradation and apoptosis in acutepromyelocytic leukemia, where it is involved in the conjugation ofthe ubiquitin-like interferon-stimulated gene 15 protein. [providedby RefSeq].


Fransen, K., et al. Hum. Mol. Genet. 19(17):3482-3488(2010)Morgan, A.R., et al. Hum. Immunol. 71(6):602-609(2010)Feng, Q., et al. Mol. Cancer Ther. 7(12):3780-3788(2008)Durfee, L.A., et al. J. Biol. Chem. 283(35):23895-23902(2008)Takeuchi, T., et al. J. Biochem. 138(6):711-719(2005)

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$ 80.00
Cat# BP14193a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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