Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   DUT Antibody (C-term) Blocking Peptide   

DUT Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P33316
Clone Names 100430342
Peptide ID 100430342
Additional Information
Gene ID 1854
Other Names Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, dUTPase, dUTP pyrophosphatase, DUT
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUT
Function This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Cellular Location Isoform 2: Nucleus.
Tissue Location Found in a variety of tissues. Isoform 3 expression is constitutive, while isoform 2 expression correlates with the onset of DNA replication (at protein level). Isoform 2 degradation coincides with the cessation of nuclear DNA replication (at protein level).
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


This gene encodes an essential enzyme of nucleotidemetabolism. The encoded protein forms a ubiquitous, homotetramericenzyme that hydrolyzes dUTP to dUMP and pyrophosphate. Thisreaction serves two cellular purposes: providing a precursor (dUMP)for the synthesis of thymine nucleotides needed for DNAreplication, and limiting intracellular pools of dUTP. Elevatedlevels of dUTP lead to increased incorporation of uracil into DNA,which induces extensive excision repair mediated by uracilglycosylase. This repair process, resulting in the removal andreincorporation of dUTP, is self-defeating and leads to DNAfragmentation and cell death. Alternative splicing of this geneleads to different isoforms that localize to either themitochondrion or nucleus. A related pseudogene is located onchromosome 19.


Takatori, H., et al. Liver Int. 30(3):438-446(2010)Quesada-Soriano, I., et al. Biochimie 92(2):178-186(2010)Chanson, A., et al. Am. J. Clin. Nutr. 89(6):1927-1936(2009)Takacs, E., et al. FEBS Lett. 583(5):865-871(2009)Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 80.00
Cat# BP14203b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions