|Other Names||COUP transcription factor 2, COUP-TF2, Apolipoprotein A-I regulatory protein 1, ARP-1, COUP transcription factor II, COUP-TF II, Nuclear receptor subfamily 2 group F member 2, NR2F2, ARP1, TFCOUP2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.|
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This gene encodes a member of the steroid thyroid hormonesuperfamily of nuclear receptors. The encoded protein is a ligandinducible transcription factor that is involved in the regulationof many different genes. Alternate splicing results in multipletranscript variants.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Feng, T., et al. Hum. Genet. 128(3):269-280(2010)Kang, J., et al. Blood 116(1):140-150(2010)Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010) :Hubert, M.A., et al. PLoS ONE 5 (2), E9417 (2010) :
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