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HMGN1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P05114
Clone Names 100517010
Peptide ID 100517010
Additional Information
Gene ID 3150
Other Names Non-histone chromosomal protein HMG-14, High mobility group nucleosome-binding domain-containing protein 1, HMGN1, HMG14
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HMGN1
Synonyms HMG14
Function Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity).
Cellular Location Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus
Research Areas
Citations (0)

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Chromosomal protein HMG14 and its close analog HMG17 (MIM163910) bind to the inner side of the nucleosomal DNA, potentiallyaltering the interaction between the DNA and the histone octamer.The 2 proteins may be involved in the process that maintainstranscribable genes in a unique chromatin conformation. Theirubiquitous distribution and relative abundance, as well as the highevolutionary conservation of the DNA-binding domain of the HMG14family of proteins, suggest that they may be involved in animportant cellular function.


Rattner, B.P., et al. Mol. Cell 34(5):620-626(2009)Cherukuri, S., et al. Mol. Biol. Cell 19(5):1816-1824(2008)Zhu, N., et al. Mol. Cell. Biol. 27(24):8859-8873(2007)Jiang, X.G., et al. Biochem. Biophys. Res. Commun. 345(4):1497-1503(2006)Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :

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$ 80.00
Cat# BP14219a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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