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DRAGON (RGMB) Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q6NW40
Other Accession Q7TQ33
Clone Names 5112166
Peptide ID 5112166
Additional Information
Gene ID 285704
Other Names RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1421c was selected from the RGMB region of human DRAGON (RGMB). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft
Research Areas
Citations (0)

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Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.


Schnichels,S., Gene Expr. Patterns 8 (1), 1-11 (2007)Metzger,M., Dev. Dyn. 234 (1), 169-175 (2005)Xia,Y., Endocrinology 146 (8), 3614-3621 (2005)

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$ 80.00
Cat# BP1421c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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