|Other Names||SLC2A4 regulator, GLUT4 enhancer factor, GEF, Huntington disease gene regulatory region-binding protein 1, HDBP-1, SLC2A4RG, HDBP1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1422b was selected from the C-term region of human HDBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'.|
|Cellular Location||Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus|
|Tissue Location||According to PubMed:14630949, expressed in heart, skeletal muscle, liver, kidney and pancreas; undetectable in lung, placenta or brain. According to PubMed:14625278, ubiquitously expressed, with lowest expression in brain and ileum|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
THDBP1 is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. This protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene.
Jones,M.R., Fertil. Steril. (2008)McGee,S.L., FASEB J. 20 (2), 348-349 (2006)Tanaka,K., J. Biol. Chem. 279 (8), 7275-7286 (2004)
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