HDBP1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NR83 |
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Clone Names | 5111867 |
Gene ID | 56731 |
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Other Names | SLC2A4 regulator, GLUT4 enhancer factor, GEF, Huntington disease gene regulatory region-binding protein 1, HDBP-1, SLC2A4RG, HDBP1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP1422b was selected from the C-term region of human HDBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC2A4RG |
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Synonyms | HDBP1 |
Function | Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'. |
Cellular Location | Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus |
Tissue Location | According to PubMed:14630949, expressed in heart, skeletal muscle, liver, kidney and pancreas; undetectable in lung, placenta or brain. According to PubMed:14625278, ubiquitously expressed, with lowest expression in brain and ileum |
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Provided below are standard protocols that you may find useful for product applications.
Background
THDBP1 is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. This protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene.
References
Jones,M.R., Fertil. Steril. (2008)McGee,S.L., FASEB J. 20 (2), 348-349 (2006)Tanaka,K., J. Biol. Chem. 279 (8), 7275-7286 (2004)
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