|Other Names||SLC2A4 regulator, GLUT4 enhancer factor, GEF, Huntington disease gene regulatory region-binding protein 1, HDBP-1, SLC2A4RG, HDBP1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1422c was selected from the Center region of human HDBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'.|
|Cellular Location||Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus|
|Tissue Location||According to PubMed:14630949, expressed in heart, skeletal muscle, liver, kidney and pancreas; undetectable in lung, placenta or brain. According to PubMed:14625278, ubiquitously expressed, with lowest expression in brain and ileum|
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Provided below are standard protocols that you may find useful for product applications.
THDBP1 is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. This protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene.
Jones,M.R., Fertil. Steril. (2008)McGee,S.L., FASEB J. 20 (2), 348-349 (2006)Tanaka,K., J. Biol. Chem. 279 (8), 7275-7286 (2004)
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