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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   MAS1 Antibody (C-term) Blocking Peptide   

MAS1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P04201
Clone Names 100517117
Peptide ID 100517117
Additional Information
Gene ID 4142
Other Names Proto-oncogene Mas, MAS1, MAS
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAS1
Synonyms MAS
Function Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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The structure of the MAS1 product indicates that itbelongs to the class of receptors that are coupled to GTP-bindingproteins and share a conserved structural motif, which is describedas a '7-transmembrane segment' following the prediction that thesehydrophobic segments form membrane-spanning alpha-helices. The MAS1protein may be a receptor that, when activated, modulates acritical component in a growth-regulating pathway to bring aboutoncogenic effects.


Yang, J.K., et al. Diabetes Care 33(10):2271-2273(2010)Reis, A.B., et al. J. Mol. Histol. 41(1):75-80(2010)Trynka, G., et al. Gut 58(8):1078-1083(2009)Iwai, M., et al. Hypertens. Res. 32(7):533-536(2009)Vaz-Silva, J., et al. Reprod Sci 16(3):247-256(2009)

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$ 80.00
Cat# BP14230b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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