Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
Lhx6 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9R1R0 |
|---|---|
| Other Accession | Q6P1H2 |
| Clone Names | 5120568 |
| Gene ID | 16874 |
|---|---|
| Other Names | LIM/homeobox protein Lhx6, LIM homeobox protein 6, LIM/homeobox protein Lhx61, Lhx6, Lhx61 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP1423a was selected from the N-term region of human Lhx6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Lhx6 |
|---|---|
| Synonyms | Lhx6.1 |
| Function | Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. |
| Cellular Location | Nucleus. |
| Tissue Location | Brain specific. Expressed by neurons in the amygdala that are activated by reproductive olfactory stimuli and project in regions of the hypothalamus involved in reproduction (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Lhx6 is a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. This protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells.
References
Lopez-Bendito,G., J. Neurosci. 28 (7), 1613-1624 (2008)Ko,S.O., Dev. Biol. 312 (1), 435-447 (2007)Jepsen,K., Nature 450 (7168), 415-419 (2007)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Shipping Information
