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AGGF1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N302 |
|---|---|
| Clone Names | 100517184 |
| Gene ID | 55109 |
|---|---|
| Other Names | Angiogenic factor with G patch and FHA domains 1, Angiogenic factor VG5Q, hVG5Q, G patch domain-containing protein 7, Vasculogenesis gene on 5q protein, AGGF1, GPATC7, GPATCH7, VG5Q |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AGGF1 |
|---|---|
| Synonyms | GPATC7, GPATCH7, VG5Q |
| Function | Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. |
| Cellular Location | Cytoplasm. Secreted. Note=Cytoplasmic in microvascular endothelial cells. Upon angiogenesis, when endothelial cell tube formation is initiated, it is secreted |
| Tissue Location | Widely expressed. Expressed in endothelial cells, vascular smooth muscle cells and osteoblasts. Expressed in umbilical vein endothelial cells and microvascular endothelial cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an angiogenic factor that promotesproliferation of endothelial cells. Mutations in this gene areassociated with a susceptibility to Klippel-Trenaunay syndrome.Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.
References
Fan, C., et al. J. Biol. Chem. 284(35):23331-23343(2009)Hu, Y., et al. Ann. Hum. Genet. 72 (PT 5), 636-643 (2008) :Gutierrez, S., et al. Am. J. Med. Genet. A 140(24):2832-2833(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Kihiczak, G.G., et al. Int. J. Dermatol. 45(8):883-890(2006)
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