|Other Names||Cyclic AMP-responsive element-binding protein 5, CREB-5, cAMP-responsive element-binding protein 5, CRE-BPa, CREB5, CREBPA|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the cAMP response element and activates transcription.|
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Provided below are standard protocols that you may find useful for product applications.
The product of this gene belongs to the CRE (cAMP responseelement)-binding protein family. Members of this family containzinc-finger and bZIP DNA-binding domains. The encoded proteinspecifically binds to CRE as a homodimer or a heterodimer withc-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator.Alternatively spliced transcript variants encoding differentisoforms have been identified.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Xu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(5):2136-2140(2010)Trynka, G., et al. Gut 58(8):1078-1083(2009)Lesch, K.P., et al. J Neural Transm 115(11):1573-1585(2008)Uhl, G.R., et al. Arch. Gen. Psychiatry 65(6):683-693(2008)
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