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FETUB Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UGM5
Clone Names 100517210
Peptide ID 100517210
Additional Information
Gene ID 26998
Other Names Fetuin-B, 16G2, Fetuin-like protein IRL685, Gugu, FETUB
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FETUB
Function Protease inhibitor required for egg fertilization. Required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity).
Cellular Location Secreted.
Tissue Location Liver and testis.
Research Areas
Citations (0)

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Background

The protein encoded by this gene is a member of the fetuinfamily, part of the cystatin superfamily of cysteine proteaseinhibitors. Fetuins have been implicated in several diversefunctions, including osteogenesis and bone resorption, regulationof the insulin and hepatocyte growth factor receptors, and responseto systemic inflammation. This protein may be secreted by cells.

References

Coen, G., et al. Am. J. Kidney Dis. 48(1):106-113(2006)Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)Wajih, N., et al. J. Biol. Chem. 279(41):43052-43060(2004)Hsu, S.J., et al. Genome 47(5):931-946(2004)Denecke, B., et al. Biochem. J. 376 (PT 1), 135-145 (2003) :

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$ 80.00
Cat# BP14246b
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