|Other Names||Proton-coupled amino acid transporter 2, Proton/amino acid transporter 2, rPAT2, Solute carrier family 36 member 2, Tramdorin-1, Slc36a2, Pat2, Tramd1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1424b was selected from the Slc36a2 region of human PAT2 (Slc36a2). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. Inhibited by sarcosine. Inhibited by L-pipecolic acid, D-pipecolic acid and isonipecotic acid.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cytoplasm|
|Tissue Location||Expressed in lung and spleen, and to a lower extent in brain, heart, kidney and skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
PAT2 is involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. It is inhibited by sarcosine.
Bermingham,J.R. Jr., Mamm. Genome 15 (2), 114-125 (2004)Rubio-Aliaga,I., J. Biol. Chem. 279 (4), 2754-2760 (2004)Boll,M., Genomics 82 (1), 47-56 (2003)Boll,M., J. Biol. Chem. 277 (25), 22966-22973 (2002)
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