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PAT2 (Slc36a2) Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8K415
Clone Names 5112871
Peptide ID 5112871
Additional Information
Gene ID 246235
Other Names Proton-coupled amino acid transporter 2, Proton/amino acid transporter 2, rPAT2, Solute carrier family 36 member 2, Tramdorin-1, Slc36a2, Pat2, Tramd1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1424b was selected from the Slc36a2 region of human PAT2 (Slc36a2). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Slc36a2
Synonyms Pat2, Tramd1
Function Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. Inhibited by sarcosine. Inhibited by L-pipecolic acid, D-pipecolic acid and isonipecotic acid.
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasm
Tissue Location Expressed in lung and spleen, and to a lower extent in brain, heart, kidney and skeletal muscle
Research Areas
Citations (0)

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Background

PAT2 is involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. It is inhibited by sarcosine.

References

Bermingham,J.R. Jr., Mamm. Genome 15 (2), 114-125 (2004)Rubio-Aliaga,I., J. Biol. Chem. 279 (4), 2754-2760 (2004)Boll,M., Genomics 82 (1), 47-56 (2003)Boll,M., J. Biol. Chem. 277 (25), 22966-22973 (2002)

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$ 80.00
Cat# BP1424b
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