|Other Names||Mitogen-activated protein kinase kinase kinase 3, MAPK/ERK kinase kinase 3, MEK kinase 3, MEKK 3, Map3k3, Mekk3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.|
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Component of a protein kinase signal transduction cascade. Map3k3 mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.
Zhang, J., et al. J. Immunol. 185(6):3554-3563(2010)Yu, L., et al. Cancer Res. 70(4):1334-1343(2010)Sun, W., et al. Cell. Signal. 21(10):1488-1494(2009)Retting, K.N., et al. Development 136(7):1093-1104(2009)Wang, X., et al. J. Immunol. 182(6):3597-3608(2009)
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