|Other Names||Atrial natriuretic peptide receptor 2, Atrial natriuretic peptide receptor type B, ANP-B, ANPR-B, NPR-B, Guanylate cyclase B, GC-B, Npr2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Widely expressed. Expressed in the columnar proliferating and prehypertrophic chondrocyte layers of the tibia|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.
Zhang, M., et al. Science 330(6002):366-369(2010)Sogawa, C., et al. Am. J. Pathol. 177(2):822-828(2010)Zhao, Z., et al. Proc. Natl. Acad. Sci. U.S.A. 106(42):18016-18021(2009)Schmidt, H., et al. Proc. Natl. Acad. Sci. U.S.A. 106(39):16847-16852(2009)Yoder, A.R., et al. Peptides 29(9):1575-1581(2008)
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