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Mouse Mark1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8VHJ5
Clone Names 110316259
Peptide ID 110316259
Additional Information
Gene ID 226778
Other Names Serine/threonine-protein kinase MARK1, ELKL motif serine/threonine-protein kinase 3, MAP/microtubule affinity-regulating kinase 1, PAR1 homolog c, Par-1c, mPar-1c, Mark1 {ECO:0000312|MGI:MGI:2664902}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mark1 {ECO:0000312|MGI:MGI:2664902}
Function Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3) (By similarity).
Cellular Location Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Appears to localize to an intracellular network.
Research Areas
Citations (0)

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Mark1 may play a role in cytoskeletal stability (By similarity).


Maussion, G., et al. Hum. Mol. Genet. 17(16):2541-2551(2008)Hezel, A.F., et al. Mol. Cell. Biol. 28(7):2414-2425(2008)Trinidad, J.C., et al. Mol. Cell Proteomics 5(5):914-922(2006)Kerns, R.T., et al. J. Neurosci. 25(9):2255-2266(2005)Okazaki, N., et al. DNA Res. 11(3):205-218(2004)

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$ 80.00
Cat# BP14269b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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