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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Lmx1a Antibody (Center) Blocking Peptide   

Lmx1a Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9JKU8
Clone Names 6012375
Peptide ID 6012375
Additional Information
Gene ID 110648
Other Names LIM homeobox transcription factor 1-alpha, LIM/homeobox protein 11, LMX-11, LIM/homeobox protein LMX1A, Lmx1a
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1426c was selected from the Center region of human Lmx1a. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Lmx1a
Function Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}
Research Areas
Citations (0)

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Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.


Mangale,V.S., Science 319 (5861), 304-309 (2008)Robertson,E.J., Development 134 (24), 4335-4345 (2007)

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$ 80.00
Cat# BP1426c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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