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Mouse Nek4 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Z1J2 |
|---|---|
| Clone Names | 110316290 |
| Gene ID | 23955 |
|---|---|
| Other Names | Serine/threonine-protein kinase Nek4, Never in mitosis A-related kinase 4, NimA-related protein kinase 4, Serine/threonine-protein kinase 2, Nek4, Stk2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Nek4 |
|---|---|
| Synonyms | Stk2 |
| Function | Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage (By similarity). Protein kinase that seems to act exclusively upon threonine residues. |
| Cellular Location | Cytoplasm. Cell projection, cilium {ECO:0000250|UniProtKB:P51957} |
| Tissue Location | Expressed ubiquitously among various organs and is up-regulated in the testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Nek4 seems to act exclusively upon threonine residues.
References
Doles, J., et al. Cancer Res. 70(3):1033-1041(2010)Forrest, A.R., et al. Genome Res. 13 (6B), 1366-1375 (2003) :Hayashi, K., et al. Biochem. Biophys. Res. Commun. 264(2):449-456(1999)Chen, A., et al. Gene 234(1):127-137(1999)
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