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Mouse Pdk3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q922H2
Clone Names 110316322
Peptide ID 110316322
Additional Information
Gene ID 236900
Other Names [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial, Pyruvate dehydrogenase kinase isoform 3, Pdk3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pdk3
Function Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species (By similarity).
Cellular Location Mitochondrion matrix.
Research Areas
Citations (0)

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Pdk3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism (By similarity).


Pagliarini, D.J., et al. Cell 134(1):112-123(2008)Blackshaw, S., et al. PLoS Biol. 2 (9), E247 (2004) :Visel, A., et al. Nucleic Acids Res. 32 (DATABASE ISSUE), D552-D556 (2004) :Mootha, V.K., et al. Cell 115(5):629-640(2003)

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$ 80.00
Cat# BP14274b
(40 western blots)
Availability: In Stock
Bulk Size
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