Mouse Plk5 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q4FZD7 |
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Clone Names | 110316341 |
Gene ID | 216166 |
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Other Names | Inactive serine/threonine-protein kinase PLK5, Polo-like kinase 5, PLK-5, Plk5 {ECO:0000250|UniProtKB:Q64702} |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Plk5 {ECO:0000250|UniProtKB:Q64702} |
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Function | Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation. |
Cellular Location | Nucleus, nucleolus. Cytoplasm |
Tissue Location | Expressed in the cerebellum, eye and brain cortex (at protein level). Expressed in highly differentiated tissues, such as brain, eyes and ovary. Not detectable in proliferating tissues, such as the colon, spleen and placenta |
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Provided below are standard protocols that you may find useful for product applications.
Background
PLK5 (Serine/threonine-protein kinase PLK5) belongs to the protein kinasesuperfamily and Ser/Thr protein kinase family and CDC5/Polo subfamily. PLK5P contains 1 POLO box domain and 1 Serine/Threonine protein kinase catalytic domain.
References
Pereira, J.D., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15957-15962(2010)Andrysik, Z., et al. Nucleic Acids Res. 38(9):2931-2943(2010)Blackshaw, S., et al. PLoS Biol. 2 (9), E247 (2004) :
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