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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Mouse Grk6 Antibody (C-term) Blocking Peptide   

Mouse Grk6 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O70293
Clone Names 110316176
Peptide ID 110316176
Additional Information
Gene ID 26385
Other Names G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6, Grk6, Gprk6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Grk6
Synonyms Gprk6
Function Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor, LRP6 during Wnt signaling (in vitro) (By similarity).
Cellular Location Membrane; Lipid-anchor.
Tissue Location Expressed in the brain in striatal neurons.
Research Areas
Citations (0)

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Specifically phosphorylates the activated forms of G protein-coupled receptors (By similarity).


Chen, M., et al. J. Biol. Chem. 284(50):35040-35048(2009)Raehal, K.M., et al. Drug Alcohol Depend 104(3):187-196(2009)Murga, C., et al. Brain Behav. Immun. 23(1):16-17(2009)Tarrant, T.K., et al. Clin. Immunol. 129(1):115-122(2008)Loniewski, K., et al. Mol. Immunol. 45(8):2312-2322(2008)

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$ 80.00
Cat# BP14287b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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