|Other Names||Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein, RAX, RX|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1428a was selected from the N-term region of human Rax. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.|
|Tissue Location||Expressed in the developing eye and weakly expressed in the adult retina|
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Provided below are standard protocols that you may find useful for product applications.
Rax plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. It binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
Voronina,V.A., Hum. Mol. Genet. 13 (3), 315-322 (2004)Mikkola,I., J. Biol. Chem. 276 (6), 4109-4118 (2001)Mathers,P.H., Cell. Mol. Life Sci. 57 (2), 186-194 (2000)
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