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Rax Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9Y2V3
Clone Names 6071570
Peptide ID 6071570
Additional Information
Gene ID 30062
Other Names Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein, RAX, RX
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1428b was selected from the C-term region of human Rax. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAX
Synonyms RX
Function Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
Cellular Location Nucleus.
Tissue Location Expressed in the developing eye and weakly expressed in the adult retina
Research Areas
Citations (0)

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Background

Rax plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. It binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.

References

Voronina,V.A., Hum. Mol. Genet. 13 (3), 315-322 (2004)Mikkola,I., J. Biol. Chem. 276 (6), 4109-4118 (2001)Mathers,P.H., Cell. Mol. Life Sci. 57 (2), 186-194 (2000)

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$ 80.00
Cat# BP1428b
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