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Mouse Tp53rk Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q99PW4
Clone Names 110328055
Peptide ID 110328055
Additional Information
Gene ID 76367
Other Names TP53-regulating kinase, Atypical serine/threonine protein kinase Tp53rk, EKC/KEOPS complex subunit Tp53rk, 36--, Nori-2, p53-related protein kinase, Tp53rk, Prpk, Trp53rk
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tp53rk
Synonyms Prpk, Trp53rk
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity). Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)

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Tp53rk is a protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation (By similarity).


Blackshaw, S., et al. PLoS Biol. 2 (9), E247 (2004) :Abe, Y., et al. J. Biol. Chem. 276(47):44003-44011(2001)

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$ 80.00
Cat# BP14294c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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