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Mouse Sgk196 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q3TUA9
Clone Names 110328075
Additional Information
Gene ID 74653
Other Names Protein O-mannose kinase, POMK, 271-, Protein kinase-like protein SgK196, Sugen kinase 196, Pomk, Sgk196
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pomk
Synonyms Sgk196
Function Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)- beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4- (phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O- mannose, suggesting that this disaccharide serves as the substrate recognition motif (By similarity).
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Research Areas
Citations (0)
citation

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Background

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.

References

Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)

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$ 277.78
Cat# BP14296b
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