Mouse Sgk196 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q3TUA9 |
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Clone Names | 110328075 |
Gene ID | 74653 |
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Other Names | Protein O-mannose kinase, POMK, 271-, Protein kinase-like protein SgK196, Sugen kinase 196, Pomk, Sgk196 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Pomk |
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Synonyms | Sgk196 |
Function | Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)- beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4- (phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O- mannose, suggesting that this disaccharide serves as the substrate recognition motif (By similarity). |
Cellular Location | Endoplasmic reticulum membrane; Single-pass type II membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
References
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)
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