|Other Names||Short-wave-sensitive opsin 1, Blue cone photoreceptor pigment, Blue-sensitive opsin, BOP, OPN1SW, BCP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||The three color pigments are found in the cone photoreceptor cells|
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This gene belongs to the G-protein coupled receptor 1family, opsin subfamily. It encodes the blue cone pigment genewhich is one of three types of cone photoreceptors responsible fornormal color vision. Defects in this gene are the cause of tritancolor blindness (tritanopia). Affected individuals lack blue andyellow sensory mechanisms while retaining those for red and green.Defective blue vision is characteristic.
Thirumuruganandham, S.P., et al. J Mol Model 15(8):959-969(2009)Ala-Laurila, P., et al. J. Biol. Chem. 284(24):16492-16500(2009)Tsutsumi, M., et al. Exp. Dermatol. 18(6):567-570(2009)Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)Fitzgibbon, J., et al. Hum. Genet. 93(1):79-80(1994)
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