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LLGL1/2 Antibody (Center S650/654) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q6P1M3
Clone Names 5021601
Peptide ID 5021601
Additional Information
Gene ID 3993
Other Names Lethal(2) giant larvae protein homolog 2, HGL, LLGL2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LLGL2
Function Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.
Cellular Location Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells
Research Areas
Citations (0)

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The lethal (2) giant larvae protein of Drosophila plays arole in asymmetric cell division, epithelial cell polarity, andcell migration. This human gene encodes a protein similar to lethal(2) giant larvae of Drosophila. In fly, the protein's ability tolocalize cell fate determinants is regulated by the atypicalprotein kinase C (aPKC). In human, this protein interacts withaPKC-containing complexes and is cortically localized in mitoticcells. Alternative splicing results in multiple transcript variantsencoding different isoforms.


Lisovsky, M., et al. Hum. Pathol. 41(6):902-909(2010)Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)Yamada, Y., et al. Atherosclerosis 207(1):144-149(2009)Lisovsky, M., et al. Mod. Pathol. 22(7):977-984(2009)

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$ 80.00
Cat# BP14311c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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