|Other Names||Cold shock domain-containing protein C2, RNA-binding protein PIPPin, CSDC2, PIPPIN|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity).|
|Cellular Location||Nucleus. Cytoplasm. Note=PIPPin-RNA complexes are located to the nucleus.|
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Provided below are standard protocols that you may find useful for product applications.
RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity).
Wu, C., et al. Proteomics 7(11):1775-1785(2007)Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :Schafer, C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4), G726-G734 (2003) :Raimondi, L., et al. J. Cell. Mol. Med. 7(1):35-42(2003)Nastasi, T., et al. Neuroreport 11(10):2233-2236(2000)
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