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TCEB2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q15370
Clone Names 81205046
Peptide ID 81205046
Additional Information
Gene ID 6923
Other Names Transcription elongation factor B polypeptide 2, Elongin 18 kDa subunit, Elongin-B, EloB, RNA polymerase II transcription factor SIII subunit B, SIII p18, TCEB2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TCEB2
Function SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene encodes the protein elongin B, which is asubunit of the transcription factor B (SIII) complex. The SIIIcomplex is composed of elongins A/A2, B and C. It activateselongation by RNA polymerase II by suppressing transient pausing ofthe polymerase at many sites within transcription units. Elongin Afunctions as the transcriptionally active component of the SIIIcomplex, whereas elongins B and C are regulatory subunits. ElonginA2 is specifically expressed in the testis, and capable of forminga stable complex with elongins B and C. The von Hippel-Lindau tumorsuppressor protein binds to elongins B and C, and thereby inhibitstranscription elongation. Two alternatively spliced transcriptvariants encoding different isoforms have been described for thisgene. Pseudogenes have been identified on chromosomes 11 and 13.


Marcsisin, S.R., et al. J. Mol. Biol. 402(5):892-904(2010)Piessevaux, J., et al. J. Biol. Chem. 283(31):21334-21346(2008)Van Herreweghe, E., et al. EMBO J. 26(15):3570-3580(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Bullock, A.N., et al. Proc. Natl. Acad. Sci. U.S.A. 103(20):7637-7642(2006)

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$ 80.00
Cat# BP14322c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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