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FZD9 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O00144
Clone Names 100507051
Peptide ID 100507051
Additional Information
Gene ID 8326
Other Names Frizzled-9, Fz-9, hFz9, FzE6, CD349, FZD9, FZD3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FZD9
Synonyms FZD3
Function Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed predominantly in adult and fetal brain, testis, eye, skeletal muscle and kidney. Moderately expressed in pancreas, thyroid, adrenal cortex, small intestine and stomach. Detected in fetal liver and kidney
Research Areas
Citations (0)

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Members of the 'frizzled' gene family encode7-transmembrane domain proteins that are receptors for Wntsignaling proteins. The FZD9 gene is located within the Williamssyndrome common deletion region of chromosome 7, and heterozygousdeletion of the FZD9 gene may contribute to the Williams syndromephenotype. FZD9 is expressed predominantly in brain, testis, eye,skeletal muscle, and kidney.


Trubiani, O., et al. J. Cell. Physiol. 225(1):123-131(2010)Saus, E., et al. J Psychiatr Res (2010) In press :Fujimoto, T., et al. Int. J. Oncol. 35(4):861-866(2009)Kim, J.G., et al. J. Korean Med. Sci. 24(3):443-447(2009)Wang, H.X., et al. Mol. Hum. Reprod. 15(1):11-17(2009)

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$ 80.00
Cat# BP14338a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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