|Other Names||Synaptotagmin-7, IPCA-7, Prostate cancer-associated protein 7, Synaptotagmin VII, SytVII, SYT7, PCANAP7|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein|
|Tissue Location||Expressed in a variety of adult and fetal tissues|
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Provided below are standard protocols that you may find useful for product applications.
Synaptotagmins, such as SYT7, are brain-specificcalcium-dependent phospholipid-binding proteins that play a role insynaptic exocytosis and neurotransmitter release. See MIM600782.
Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Fukuda, M., et al. Biochem. J. 365 (PT 1), 173-180 (2002) :Caler, E.V., et al. J. Exp. Med. 193(9):1097-1104(2001)Mizutani, A., et al. J. Biol. Chem. 275(13):9823-9831(2000)
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