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TDO2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P48775 |
|---|---|
| Clone Names | 100324101 |
| Gene ID | 6999 |
|---|---|
| Other Names | Tryptophan 2, 3-dioxygenase {ECO:0000255|HAMAP-Rule:MF_03020}, TDO {ECO:0000255|HAMAP-Rule:MF_03020}, 1131111 {ECO:0000255|HAMAP-Rule:MF_03020}, Tryptamin 2, 3-dioxygenase {ECO:0000255|HAMAP-Rule:MF_03020}, Tryptophan oxygenase {ECO:0000255|HAMAP-Rule:MF_03020}, TO {ECO:0000255|HAMAP-Rule:MF_03020}, TRPO {ECO:0000255|HAMAP-Rule:MF_03020}, Tryptophan pyrrolase {ECO:0000255|HAMAP-Rule:MF_03020}, Tryptophanase {ECO:0000255|HAMAP-Rule:MF_03020}, TDO2 {ECO:0000255|HAMAP-Rule:MF_03020}, TDO |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TDO2 {ECO:0000255|HAMAP-Rule:MF_03020} |
|---|---|
| Synonyms | TDO |
| Function | Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Tryptophan 2,3-dioxygenase (EC 1.13.11.11) plays a role incatalyzing the first and rat-limiting step in the kynureninepathway, the major pathway of tryptophan metabolism.[supplied byOMIM].
References
Capece, L., et al. J. Biol. Inorg. Chem. 15(6):811-823(2010)Schmidt, S.K., et al. Eur. J. Immunol. 39(10):2755-2764(2009)Roeske, D., et al. Mol. Psychiatry (2009) In press :Miller, C.L., et al. Schizophr. Res. 113 (2-3), 259-267 (2009) :Fukumura, E., et al. J. Biochem. 145(4):505-515(2009)
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