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H Cadherin (CDH13) Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P55290
Clone Names 70730039
Additional Information
Gene ID 1012
Other Names Cadherin-13, Heart cadherin, H-cadherin, P105, Truncated cadherin, T-cad, T-cadherin, CDH13, CDHH
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1434a was selected from the N-term region of human CDH13. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDH13
Synonyms CDHH
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Location Highly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord
Research Areas
Citations (0)
citation

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Background

CDH13 is a member of the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region but, unlike the typical cadherin superfamily member, lacks the highly conserved cytoplasmic region. This particular cadherin is a putative mediator of cell-cell interaction in the heart and may act as a negative regulator of neural cell growth.

References

Qian,Z.R., Mod. Pathol. 20 (12), 1269-1277 (2007)Tsou,J.A., Mol. Cancer 6, 70 (2007)

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$ 277.78
Cat# BP1434a
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