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TOLLIP Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9H0E2
Clone Names 100430194
Peptide ID 100430194
Additional Information
Gene ID 54472
Other Names Toll-interacting protein, TOLLIP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin- ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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This gene encodes a ubiquitin-binding protein thatinteracts with several Toll-like receptor (TLR) signaling cascadecomponents. The encoded protein regulates inflammatory signalingand is involved in interleukin-1 receptor trafficking and in theturnover of IL1R-associated kinase.


Han, S., et al. Hum. Immunol. 71(7):727-730(2010)Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)

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$ 80.00
Cat# BP14351b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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