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SF1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q15637
Clone Names 100430333
Additional Information
Gene ID 7536
Other Names Splicing factor 1, Mammalian branch point-binding protein, BBP, mBBP, Transcription factor ZFM1, Zinc finger gene in MEN1 locus, Zinc finger protein 162, SF1, ZFM1, ZNF162
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SF1
Synonyms ZFM1, ZNF162
Function Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.
Cellular Location Nucleus.
Tissue Location Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart
Research Areas
Citations (0)
citation

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Background

This gene encodes a nuclear pre-mRNA splicing factor. Theencoded protein specifically recognizes the intron branch pointsequence and is required for the early stages of spliceosomeassembly. Alternate splicing results in multiple transcriptvariants.

References

Jeyabalan, J., et al. PLoS ONE 5 (5), E10646 (2010) :Corsini, L., et al. J. Biol. Chem. 284(1):630-639(2009)Rino, J., et al. Mol. Cell. Biol. 28(9):3045-3057(2008)Olejnik-Schmidt, A.K., et al. Arch. Virol. 153(5):983-990(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

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$ 277.78
Cat# BP14357c
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