|Other Names||Ras suppressor protein 1, RSP-1, Rsu-1, RSU1, RSP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that is involved in the Rassignal transduction pathway, growth inhibition, and nerve-growthfactor induced differentiation processes, as determined in mouseand human cell line studies. In mouse, the encoded protein wasinitially isolated based on its ability to inhibit v-Rastransformation. Multiple alternatively spliced transcript variantsfor this gene have been reported; one of these variants was foundonly in glioma tumors.
Rose, J. Phd, et al. Mol. Med. (2010) In press :Dougherty, G.W., et al. Eur. J. Cell Biol. 87 (8-9), 721-734 (2008) :Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Dougherty, G.W., et al. Exp. Cell Res. 306(1):168-179(2005)
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