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IL9R Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q01113
Clone Names 100507326
Additional Information
Gene ID 3581
Other Names Interleukin-9 receptor, IL-9 receptor, IL-9R, CD129, IL9R
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL9R
Function Plays an important role in the immune response against parasites by acting as a receptor of IL9.
Cellular Location Cell membrane; Single-pass type I membrane protein. Secreted
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a cytokine receptorthat specifically mediates the biological effects of interleukin 9(IL9). The functional IL9 receptor complex requires this protein aswell as the interleukin 2 receptor, gamma (IL2RG), a common gammasubunit shared by the receptors of many different cytokines. Theligand binding of this receptor leads to the activation of variousJAK kinases and STAT proteins, which connect to different biologicresponses. This gene is located at the pseudoautosomal regions of Xand Y chromosomes. Genetic studies suggested an association of thisgene with the development of asthma. Multiple pseudogenes onchromosome 9, 10, 16, and 18 have been described. Alternativelyspliced transcript variants have been found for this gene.

References

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :McCanlies, E.C., et al. J. Occup. Environ. Med. 52(7):680-684(2010)Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :

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$ 277.78
Cat# BP14364c
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