IL9R Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q01113 |
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Clone Names | 100507326 |
Gene ID | 3581 |
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Other Names | Interleukin-9 receptor, IL-9 receptor, IL-9R, CD129, IL9R |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | IL9R |
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Function | Plays an important role in the immune response against parasites by acting as a receptor of IL9. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Secreted |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a cytokine receptorthat specifically mediates the biological effects of interleukin 9(IL9). The functional IL9 receptor complex requires this protein aswell as the interleukin 2 receptor, gamma (IL2RG), a common gammasubunit shared by the receptors of many different cytokines. Theligand binding of this receptor leads to the activation of variousJAK kinases and STAT proteins, which connect to different biologicresponses. This gene is located at the pseudoautosomal regions of Xand Y chromosomes. Genetic studies suggested an association of thisgene with the development of asthma. Multiple pseudogenes onchromosome 9, 10, 16, and 18 have been described. Alternativelyspliced transcript variants have been found for this gene.
References
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :McCanlies, E.C., et al. J. Occup. Environ. Med. 52(7):680-684(2010)Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
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