BLVRA Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P53004 |
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Clone Names | 100517097 |
Gene ID | 644 |
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Other Names | Biliverdin reductase A, BVR A, Biliverdin-IX alpha-reductase, BLVRA, BLVR, BVR |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | BLVRA (HGNC:1062) |
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Function | Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor (PubMed:8631357, PubMed:8424666, PubMed:7929092). Uses the reactants NADH or NADPH depending on the pH; NADH is used at the acidic pH range (6-6.9) and NADPH at the alkaline range (8.5-8.7) (PubMed:8631357, PubMed:8424666, PubMed:7929092). NADPH, however, is the probable reactant in biological systems (PubMed:7929092). |
Cellular Location | Cytoplasm, cytosol |
Tissue Location | Liver. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Biliverdin reductases, such as BLVRA (EC 1.3.1.24),catalyze the conversion of biliverdin to bilirubin in the presenceof NADPH or NADH (Komuro et al., 1996 [PubMed 8950184]).[suppliedby OMIM].
References
Gibbs, P.E., et al. FASEB J. 24(9):3239-3254(2010)Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)Jansen, T., et al. J. Mol. Cell. Cardiol. 49(2):186-195(2010)Miralem, T., et al. J. Biol. Chem. 285(17):12551-12558(2010)Goven, D., et al. PLoS ONE 5 (5), E10886 (2010) :
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