|Other Names||60S ribosomal protein L8, RPL8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the large ribosomal subunit.|
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Provided below are standard protocols that you may find useful for product applications.
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 60S subunit. The protein belongsto the L2P family of ribosomal proteins. It is located in thecytoplasm. In rat, the protein associates with the 5.8S rRNA, verylikely participates in the binding of aminoacyl-tRNA, and is aconstituent of the elongation factor 2-binding site at theribosomal subunit interface. Alternatively spliced transcriptvariants encoding the same protein exist. As is typical for genesencoding ribosomal proteins, there are multiple processedpseudogenes of this gene dispersed through the genome. [provided byRefSeq].
Salas, S., et al. Int. J. Cancer 125(4):851-860(2009)Stelzl, U., et al. Cell 122(6):957-968(2005)Andersen, J.S., et al. Nature 433(7021):77-83(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
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